CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 80 enrolled
Drug / intervention
Exercise Training +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04199182
NCT04199182N/ACompleted

Exploring the Effects of Exercise Training on PTSD Symptoms and Physical Health in Older Veterans With PTSD

VA Office of Research and Development·interventional·Posted Dec 13, 2019·Updated Mar 25, 2026

In Brief

A clinical study evaluating Exercise Training and Healthy Aging Attention Control (HA-ATC) for Post-traumatic Stress Disorder. Completed, enrolled 80 participants across 1 site.

Detailed Summary

Posttraumatic stress disorder (PTSD) is prevalent among military Veterans and is more than just a psychological condition; PTSD has profound negative impacts on health, function, and quality of life. Older Veterans are the largest patient population served by the Veterans Health Administration (VHA), and many have lived with PTSD for 40+ years. Veterans with PTSD engage in low levels of physical activity and spend much of their time in sedentary activities, adding to their risk of physical disability. The benefits of exercise on mental health and physical well-being in older adults are well-substantiated, but the effects of exercise training on late-life PTSD symptoms is a new area of study. This study is designed to examine the effects of 6 months of supervised exercise training on PTSD symptoms and PTSD-related conditions (e.g., functional impairment, sleep) in 188 older Veterans with PTSD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedDec 13, 2019
Enrollment StartJun 7, 2021
Primary CompletionFeb 10, 2025
Study CompletionFeb 28, 2025
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 6.6 years ago

Interventions

Exercise Trainingbehavioral

A multi-component group exercise intervention that emphasizes functional training. Duration is 6 months, and frequency is 3x per week.

Healthy Aging Attention Control (HA-ATC)other

Participants in the HA-ATC group will receive a health education program modeled on the "10 Keys to Healthy Aging" curriculum and the National Council on Aging's "Aging Mastery Program." HA-ATC will include an 8-week face-to-face group program followed by bi-weekly sessions for the remaining 4 months.