At a glance
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A Randomized Controlled Trial Examining the Neurocognitive Benefits of a Nationally Available Weight Management Program
In Brief
A Phase 4 clinical trial evaluating WW (formerly Weight Watchers) and Waitlist for Overweight and Obesity. Completed, enrolled 61 participants across 1 site.
Detailed Summary
This study will assess whether weight loss induced through diet and physical activity can change neural responses to high- and low-calorie food images. In addition, it will evaluate whether weight loss can improve neural function when performing the N-back task, a measure of working memory. Findings will address notable gaps in the literature by testing whether a scalable weight loss intervention can help protect and improve neurocognitive functioning and brain health in individuals with obesity. This study will also provide important information about the effects of weight loss on neuroplasticity in brain regions crucial for memory and cognitive functioning, which will help to inform future interventions aimed at promoting brain health.
Study Details
Timeline
Interventions
The WW intervention will consist of weekly group workshops for 16 weeks with WW Coaches and Guides.
The waitlist group will have a 16-week waitlist period. After the waitlist period, they will be offered the WW intervention