CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Oral soft tissues biopsiesother
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04202822
NCT04202822N/ACompleted
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Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis Part I - Gene Expression and Cellular Behaviour 24-hours After Injury

University of Roma La Sapienza·interventional·Posted Dec 18, 2019·Updated Feb 19, 2020

In Brief

A clinical study evaluating Oral soft tissues biopsies for Wound Surgical and 2 related conditions. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The purpose of the present study is to observe and compare -through a biomolecular analysis- the differences in the gene expression and cellular behavior in the early wound healing process -24 hours after injury- between the following three oral tissues: alveolar mucosa, buccal gingiva and palatal tissue. The main hypothesis is that there is a difference in the gene expression and in the cellular behaviour between the three oral tissues studied and this difference can be observed at 24 hours post-injury.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsWound Surgical, Wound Heal, Oral Soft Tissue Conditions
CountriesItaly
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedDec 18, 2019
Enrollment StartApr 1, 2019
Primary CompletionJun 6, 2019
Study CompletionJun 13, 2019
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 6.5 years ago

Interventions

Oral soft tissues biopsiesother

Oral soft tissues biopsies (alveolar mucosa, buccal gingiva, and palatal tissue) will be harvested by the examiner at the time of the surgery (immediately before to start the surgical procedure -T0) and 24 hours after surgery (T24) at the level of the vertical released incisions (VRIs) with a biopsy punch with plunger of 2.0 mm diameter.