CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 12 enrolled
Drug / intervention
Activated charcoal and Tap Water +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04204772
NCT04204772Early Ph 1Completed
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A Pilot Feasibility Study of Activated Charcoal in Healthy Adult Volunteers

Masonic Cancer Center, University of Minnesota·interventional·Posted Dec 19, 2019·Updated Oct 26, 2023

In Brief

A Early Phase 1 clinical trial evaluating Activated charcoal and Tap Water and Activated Charcoal and Apple Juice for Healthy Adult Volunteers. Completed, enrolled 12 participants across 1 site.

Detailed Summary

This is a pilot study designed to test feasibility, tolerability, and safety of medical grade oral Activated Charcoal (AC) in 12 healthy volunteers. To determine the two most palatable and tolerable AC combinations. There will be a total of 4 combinations (2 AC doses and 2 solutions) in stage 1. Each participant will drink an assigned combination every day for 3 consecutive days (Monday, Tuesday, Wednesday, "M/T/W") and switch to a different assigned combination M/T/W the following week. AC solution assignments will be defined before the study using a balanced incomplete block design. Each subject will rate their experience using a 5-point scale every day for the 12 days they are on study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy Adult Volunteers
CountriesUnited States
CollaboratorsNational Center for Advancing Translational Sciences (NCATS)

Timeline

Early Ph 1CompletedFinished
2020202120222023202420252026
First PostedDec 19, 2019
Enrollment StartJan 22, 2020
Primary CompletionMar 31, 2021
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 6.5 years ago

Interventions

Activated charcoal and Tap Waterbiological

12 grams of AC mixed with Tap water or 25 grams of AC mixed with Tap water

Activated Charcoal and Apple Juicebiological

12 grams of AC with Apple Juice or 25 grams of AC with Apple Juice