CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 204 enrolled / 204 target
Drug / intervention
Standard coffee +2 moredietary
Likely dose
30 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04205058
NCT04205058N/ACompletedHigh Momentum (2.6/mo)Completion was 17mo ago
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Coffee After Pancreatic Surgery - a Randomised, Single Blinded, Placebo-controlled Trial

Azienda Ospedaliera Universitaria Integrata Verona·interventional·Posted Dec 19, 2019·Updated Jun 8, 2026

In Brief

A clinical study evaluating Standard coffee, Caffeine-free coffee, and 1 other intervention for Postoperative Ileus and 3 related conditions. Completed, enrolled 204 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

Postoperative ileus is a common complication after major abdominal surgery. A positive effect of coffee to bowel movement has been described after colorectal and gynecologic interventions. The objective of this randomised controlled trial is to investigate whether the implementation of a fast track protocol with early coffee consumption accelerates the recovery of bowel function after pancreaticoduodenectomy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostoperative Ileus, Postoperative Complications, Bowel Dysfunction, Pancreatic Diseases
CountriesItaly
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedDec 19, 2019
Enrollment StartJan 5, 2020
Primary CompletionJan 5, 2025
TodayJul 2, 2026
Enrollment to primary: 5 yearsPosted 6.5 years ago

Arms & Interventions

standard coffeeexperimental

Hot standard coffee with caffeine (one 30 mL espresso cup twice a day, from postoperative day one to first bowel movement or postoperative day three).

Dietary Supplement: Standard coffee
caffeine-free coffeeplacebo_comparator

Hot caffeine-free coffee (one 30 mL espresso cup twice a day, from postoperative day one to first bowel movement or postoperative day three).

Dietary Supplement: Caffeine-free coffee
watersham_comparator

Hot water (one 30 mL espresso cup twice a day, from postoperative day one to first bowel movement or postoperative day three).

Dietary Supplement: Drinking water

Interventions

Standard coffeedietary

One 30 mL espresso cup administered twice a day (08.00 a.m. and 02.00 p.m.).

Caffeine-free coffeedietary

One 30 mL espresso cup administered twice a day (08.00 a.m. and 02.00 p.m.).

Drinking waterdietary

One 30 mL espresso cup administered twice a day (08.00 a.m. and 02.00 p.m.).