CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 120 enrolled
Drug / intervention
silver nano particulate solution mixed with calcium hydroxide powder +1 morecombination
Likely dose
silver nano particulate solution mixed with calcium hydroxide powder 1mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04213716
NCT04213716Phase 2Completed
CompareCT.gov

Comparison of the Efficacy of Calcium Hydroxide Combined With Silver Nano Particulate and Conventional Calcium Hydroxide Intra Canal Medications on Post-Operative Pain in Symptomatic Root Canal Treatment Failure Cases: A Randomized Clinical Trial Therapeutic Study

Cairo University·interventional·Posted Dec 30, 2019·Updated Jan 2, 2020

In Brief

A Phase 2 clinical trial evaluating silver nano particulate solution mixed with calcium hydroxide powder and conventional calcium hydroxide for Retreatment and 17 related conditions. Completed, enrolled 120 participants across 1 site.

Detailed Summary

The aim of this study is to measure and compare the effectiveness of nanosilver combined calcium hydroxide and conventional calcium hydroxide intracanal medications in reducing postoperative pain in patients with Symptomatic Root Canal treatment Failure .

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRetreatment, Root Canal Retreatment, Nonsurgical Retreatment, Endodontic Failure, Symptomatic Endodontic Failure, Nanosilver, Intracanal Medicament, Intracanal Dressing, AgNPs, Calcium Hydroxide, Ca (OH)2, Discomfort, Pain, Flare up, Postoperative, Ache, Post-operative, Post Obturation
CountriesEgypt
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 30, 2019
Enrollment StartJun 15, 2015
Primary CompletionJun 1, 2016
Study CompletionDec 12, 2016
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 6.5 years ago

Interventions

silver nano particulate solution mixed with calcium hydroxide powdercombination

1ml of nanosilver solution 30ppm concentration mixed with 100 mg of calcium hydroxide powder used as intracanal medication

conventional calcium hydroxidecombination

1ml of distilled water mixed with 100 mg of calcium hydroxide powder and used as intracanal medication after root canal retreatment