CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 35 enrolled
Drug / intervention
Probenecid or placebo single administrationdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04218357
NCT04218357Phase 1Completed

Probenecid as Pharmacotherapy for Alcohol Use Disorder

Brown University·interventional·Posted Jan 6, 2020·Updated Feb 27, 2025

In Brief

A Phase 1 clinical trial evaluating Probenecid or placebo single administration for Alcohol Use Disorder. Completed, enrolled 35 participants across 1 site.

Detailed Summary

The design is a randomized, within-subject, crossover, double-blind, placebo-controlled human alcohol laboratory study with one oral dose of 2g probenecid or placebo administered in two laboratory sessions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
2020202120222023202420252026
First PostedJan 6, 2020
Enrollment StartDec 2, 2020
Primary CompletionMay 16, 2023
Study CompletionMay 20, 2023
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 6.5 years ago

Interventions

Probenecid or placebo single administrationdrug

study drug administration with alcohol in the laboratory