CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 105 enrolled
Drug / intervention
Single Bond Universal +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04225247
NCT04225247Phase 3Completed

Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity A Randomized Clinical Trial

Dow University of Health Sciences·interventional·Posted Jan 13, 2020·Updated Jan 18, 2020

In Brief

A Phase 3 clinical trial evaluating Single Bond Universal, Bifluorid 12, and 1 other intervention for Dentin Hypersensitivity. Completed, enrolled 105 participants across 1 site.

Detailed Summary

The world lacks a gold standard treatment for treating dentin hypersensitivity. Fluoride varnish is most commonly used as a treatment but it causes temporary discoloration of tooth structure and may cause irritation or burning of gums when it comes in contact with gums. Seventh generation bonding agents are less technique sensitive and are easy to use. The present study aims to find out the better seventh generation bonding agent as a treatment option for sensitivity. A total of 105 patients with dentin hypersensitivity are randomized into three groups. Scaling and root debridement are performed for all the groups. This study compares two seventh generation bonding agents and taking fluoride varnish as control group.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPakistan
Collaborators--

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedJan 13, 2020
Enrollment StartMar 7, 2018
Primary CompletionOct 7, 2018
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 6.5 years ago

Interventions

Single Bond Universaldrug

Single bond universal (by 3M ESPE) is a seventh generation bonding agents used as desensitizers in the present study.

Bifluorid 12drug

it is a fluoride varnish by VOCO.

Xeno V+drug

Xeno V+ (by Dentsply) is a seventh generation bonding agents used as desensitizers in the present study.