At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 168 enrolled
Drug / intervention
Trospium +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence
In Brief
A Phase 4 clinical trial evaluating Trospium and Placebo oral tablet for Urgency Urinary Incontinence. Completed, enrolled 168 participants across 1 site.
Detailed Summary
This is a randomized double-blind crossover trial of trospium and placebo in women with urgency urinary incontinence, with evaluation (history, physical, incontinence evaluation and brain MRI) at baseline, and after each course of therapy. The investigators will evaluate functional brain changes in relation to bladder improvement in order to improve our knowledge of the brain's role in the continence mechanism.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsUrgency Urinary Incontinence
CountriesUnited States
CollaboratorsNational Institute on Aging (NIA)
Timeline
Phase 4CompletedFinished
2020202120222023202420252026
First PostedJan 2020
Enrollment StartFeb 2020
Primary CompletionFeb 2025
Study CompletionOct 2025
TodayJul 2026
First PostedJan 13, 2020
Enrollment StartFeb 13, 2020
Primary CompletionFeb 28, 2025
Study CompletionOct 30, 2025
TodayJul 2, 2026
Enrollment to primary: 5.0 yearsPosted 6.5 years ago
Interventions
Trospiumdrug
Drug to treat overactive bladder
Placebo oral tabletdrug
Placebo tablet containing no active drug