CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Nicotine +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04231539
NCT04231539N/ACompleted

Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids[SALTVAPE Study]

Roswell Park Cancer Institute·interventional·Posted Jan 18, 2020·Updated Oct 31, 2025

In Brief

A clinical study evaluating Nicotine, Vaporizer Device, and 3 other interventions for Nicotine Dependence. Completed, enrolled 15 participants across 1 site.

Detailed Summary

This trial studies activity of time (pharmacokinetics), subjective effects, and abuse liability of nicotine salt-based vaping products with tobacco or e-liquids. This study aims to determine and compare the levels of nicotine delivered to the bloodstream from nicotine salt and free-base nicotine e-liquid solutions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJan 18, 2020
Enrollment StartFeb 18, 2020
Primary CompletionJul 10, 2024
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 6.5 years ago

Interventions

Nicotinedrug

Vape Free-Low nicotine unflavored

Vaporizer Devicedevice

Take puffs from vaporizer filled with different flavors

Salt-HIgh Nicotine Unflavored (Product B)drug

Vape Salt-High nicotine unflavored

Free-Low Nicotine Tobacco Flavored (Product C)drug

Vape Free-Low Nicotine Tobacco

Salt-High Nicotine Tobacco Flavored (Product D)drug

Vape Salt-High Tobacco