CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
Amnio Excel + weekly +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04233580
NCT04233580N/ACompleted

Characterization of AmnioExcel Plus in Two Treatment Paradigms

University of Texas Southwestern Medical Center·interventional·Posted Jan 18, 2020·Updated Jul 24, 2023

In Brief

A clinical study evaluating Amnio Excel + weekly and Amnio Excel + max every 2 weeks for Diabetic Foot Ulcer. Completed, enrolled 40 participants across 1 site.

Detailed Summary

The Investigators plan to evaluate healing in two cohorts of patients with diabetic foot wounds (n=20) that receive optimal treatment including serial wound debridement and off-loading with a boot or postop shoe and AmnioEXCEL+. In one cohort, AmnioEXCEL+ will be applied weekly at study visits and in the second cohort, AmnioEXCEL+ will be applied maximum every 2 weeks (PRN, in the case that the wound requires debridement at a visit not intended for AE+ application, the wound will be treated as SOC). In addition, the Investigators will collect data on other potential confounding factors that could affect healing such as antibiotic, anti-fungal and anti-infective medications, tobacco, comorbidities, diabetes control, infection, perfusion, and activity. Wound healing, including wound size and adverse events will be evaluated.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJan 18, 2020
Enrollment StartJul 9, 2020
Primary CompletionApr 6, 2021
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 6.5 years ago

Interventions

Amnio Excel + weeklydevice

Amnio Excel + weekly

Amnio Excel + max every 2 weeksdevice

Amnio Excel + max every 2 weeks