CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 94 enrolled
Drug / intervention
NIFEdipine ER +1 moredrug
Likely dose
NIFEdipine ER 30mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04236258
NCT04236258Phase 4Completed

A Randomized Controlled Trial Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period

Brigham and Women's Hospital·interventional·Posted Jan 22, 2020·Updated Nov 30, 2022

In Brief

A Phase 4 clinical trial evaluating NIFEdipine ER and Enalapril for Hypertension in Pregnancy and 4 related conditions. Completed, enrolled 94 participants across 1 site.

Detailed Summary

This study evaluates whether nifedipine or enalapril is better at decreasing the amount of medical resources used in the postpartum period by women who have high blood pressure in pregnancy and the postpartum period. Half of participants will receive enalapril while the other half will receive enalapril. We will compare the two groups in the amount of medical resources used which we are defining as prolonged hospitalizations, unscheduled medical visits and/or hospital readmissions in the postpartum period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedJan 22, 2020
Enrollment StartJan 24, 2020
Primary CompletionJun 30, 2021
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 6.4 years ago

Interventions

NIFEdipine ERdrug

Postpartum women with high blood pressure will be randomized to receive nifedipine extended release 30mg daily as their starting antihypertensive.

Enalaprildrug

Postpartum women with high blood pressure will be randomized to receive enalapril 10 mg daily as their starting antihypertensive.