CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 151 enrolled
Drug / intervention
Desflurane Inhalational agentdrug
Likely dose
Not stated in record
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Search/NCT04238806
NCT04238806N/ACompleted
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An Investigation of the Association Between Desflurane Inhalational Agent, Serum Brain Natriuretic Peptide (BNP) Levels and Clinical Outcomes During Coronary Artery Bypass Graft (CABG) Surgery

Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital·interventional·Posted Jan 23, 2020·Updated Jan 23, 2020

In Brief

A clinical study evaluating Desflurane Inhalational agent for Brain Natriuretic Peptide and 5 related conditions. Completed, enrolled 151 participants.

Detailed Summary

During coronary artery bypass grafting (CABG) operations with cardiopulmonary bypass (CPB), the use of desflurane continuously or intermittently may have effects on serum brain natriuretic peptide (BNP) levels. The aim is to investigate the association between desflurane, serum BNP values, and clinical outcomes during CABG operations. In a prospective, randomized, double-blinded study, desflurane inhalational anesthesia was administered either continuously or intermittently (Group 1; n=60 versus Group 2; n=62). The preoperative and postoperative BNP levels at 24, 48 and 72 hours after surgery were collected. Outcomes were recorded.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBrain Natriuretic Peptide, Coronary Artery Bypass Graft Surgery, Cardiac Surgery, Cardiopulmonary Bypass, Desflurane, Outcome
Countries--
CollaboratorsTrakya University Teaching and Research Hospital

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJan 23, 2020
Enrollment StartSep 1, 2013
Primary CompletionAug 31, 2014
Study CompletionSep 30, 2014
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 6.4 years ago

Interventions

Desflurane Inhalational agentdrug

Desflurane inhalational agent administration during the whole cardiac surgical operation with cardiopulmonary bypass versus administration of desflurane inhalational agent before and after cardiopulmonary bypass during the whole period of cardiac surgical operation.