At a glance
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Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain Injury
In Brief
An observational study evaluating Transcranial Doppler for Traumatic Brain Injury and 2 related conditions. Completed, enrolled 29 participants across 1 site.
Detailed Summary
Various methods have been studied to evaluate autoregulation. However, there is currently no universally accepted technique to assess integrity of the cerebral autoregulation neurovascular system. In the last decade, significant progress has been achieved in developing methods to assess cerebral autoregulation by quantifying cross-correlation between spontaneous oscillations in CBF or oxygenation and similar oscillations in arterial blood pressure. In this study the investigators will analyze the relationship between spontaneous fluctuations in mean arterial blood pressure and cerebral blood flow velocity or cerebral regional oxygenation to investigate two novel methods for measuring cerebral autoregulation, Transfer Function Analysis and Wavelet Coherence after acute pediatric brain injury.
Study Details
Timeline
Interventions
Record flow velocity tracing of middle cerebral artery using a transcranial doppler.