CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 512 enrolled
Drug / intervention
Erenumab +1 moredrug
Likely dose
Erenumab 140 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04252742
NCT04252742Phase 4Completed

Comprehensive Assessment of Erenumab Efficacy in Subjects With High Frequency Episodic Migraine With at Least 1 Previously Failed Preventive Treatment: a Global, Double-blind, Placebo-controlled Phase 4 Study

Amgen·interventional·Posted Feb 5, 2020·Updated Mar 31, 2026

In Brief

A Phase 4 clinical trial evaluating Erenumab and Placebo for Migraine. Completed, enrolled 512 participants across 91 sites in 9 countries.

Detailed Summary

The primary objective of this study is to evaluate the treatment benefit of erenumab on headache duration of at least moderate pain intensity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
CountriesBulgaria, Czechia, Hungary, Italy, Poland, Portugal, Romania, Spain, United States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedFeb 5, 2020
Enrollment StartSep 15, 2020
Primary CompletionOct 26, 2023
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 6.4 years ago

Interventions

Erenumabdrug

140 mg, 2 consecutive injections of 70 mg

Placebodrug

2 consecutive injections