CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 77 enrolled / 77 target
Drug / intervention
progressive resistance trainingbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04255745
NCT04255745N/ACompletedOn Track (1.0/mo)Completion was 24mo ago

The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia

University of Illinois at Chicago·interventional·Posted Feb 5, 2020·Updated Jun 2, 2026

In Brief

A clinical study evaluating progressive resistance training for Sarcopenia and 2 related conditions. Completed, enrolled 77 participants across 1 site.

Detailed Summary

Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal. This randomized control intervention pilot study will provide new evidence of the unexplored relationship between muscle strength and high BP in sarcopenia, and experimentally test the effects of an evidence-based progressive resistance training intervention on BP, while also examining reversibility to identify muscle strength as a non-pharmacological target for BP control in older sarcopenic adults.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedFeb 5, 2020
Enrollment StartJan 27, 2020
Primary CompletionJun 30, 2024
Study CompletionMay 1, 2025
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 6.4 years ago

Arms & Interventions

Assessment-only controlno_intervention

30 Assessment-only control group will be mailed (standard or electronic) NIH/National Institutes on Aging (NIA) Go4Life® educational materials once a month for 3 months. Exercise logs documenting weekly exercise activities, duration, time and effort will be requested to be sent back.

Interventionexperimental

60 Intervention group will receive 12 weeks of supervised resistance training following the American Heart Association and American College of Sports Medicine guidelines for older adults. Exercises will include a mixture of upper-body and lower body strength exercises. Training load will be determined based on initial 1-repetition maximum tests (1-RM). Initial exercise load will start off at low resistance (40-50% 1RM) with more frequent repetitions per exercise, and will gradually increase weight load and intensity over the exercise training period.

Behavioral: progressive resistance training

Interventions

progressive resistance trainingbehavioral

Individual, tailored, progressive muscle strength and function intervention