CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 34,000 enrolled
Drug / intervention
General practitioner and Patient receive informations related to PPI deprescribing. +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04255823
NCT04255823N/ACompleted

Efficacy of a Multi-faceted Intervention to Deprescribe Proton Pump Inhibitors (PPI) in Primary Care: a Population-based, Pragmatic, Cluster-randomized Controlled Trial.

Nantes University Hospital·interventional·Posted Feb 5, 2020·Updated Apr 22, 2024

In Brief

A clinical study evaluating General practitioner and Patient receive informations related to PPI deprescribing. and Only General practitioner receive informations related to PPI deprescribing. for Proton Pump Inhibitors and Deprescription. Completed, enrolled 34,000 participants across 1 site.

Detailed Summary

Deprescribing is defined as "the process of withdrawal of an inappropriate medication, supervised by a health care professional with the goal of managing the polypharmacy and improving outcomes". Inappropriate use of proton pump inhibitors (PPI) is associated with severe adverse drug reactions and a major economic impact. Deprescribing should be considered when inappropriate prescription of PPI is identified. DeprescrIPP is a pragmatic population-based cluster-randomized trial conducted in primary care. It will assess the efficacy and effectiveness of a multi-faceted intervention (on patients and general practitioners) to deprescribe PPI.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedFeb 5, 2020
Enrollment StartSep 29, 2020
Primary CompletionDec 15, 2021
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 6.4 years ago

Interventions

General practitioner and Patient receive informations related to PPI deprescribing.other

General practitioner will receive a sensibilization and an algorithm related to PPI deprescribing. Their patients will receive any informations (patient information material on PPI deprescribing)

Only General practitioner receive informations related to PPI deprescribing.other

General practitioner will receive the sensibilization and an algorithm related to PPI deprescribing. Their patients will not receive any informations.