CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 340 enrolled
Drug / intervention
Psychosocial treatmentbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04257214
NCT04257214N/AActive

Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine

Philadelphia College of Osteopathic Medicine·interventional·Posted Feb 5, 2020·Updated Jul 31, 2025

In Brief

A clinical study evaluating Psychosocial treatment for Opioid Use Disorder. Active but no longer recruiting, targeting 340 participants across 5 sites.

Detailed Summary

Current clinical guidelines for medication assisted treatment (MAT) of opioid use disorder (OUD) recommend that treatment include a psychosocial component to help address psychological factors related to addiction. However, a knowledge gap exists regarding the most effective forms of psychosocial intervention and what interventions are most effective for different types of patients. This gap represents a significant barrier to the widespread implementation of effective office-based opioid treatment (OBOT) with buprenorphine, which is important to improving opioid treatment and responding to the critical needs of individuals living with OUD. The overarching goal of this patient-centered research is to address the diverse needs and preferences of OUD patients in regards to psychosocial approaches and to overcome the "one-size-fits-all" strategies that are typically used to treat OUD. Importantly, investigators arrived at this goal, in part, through collaboration and consultation with former patients who have received different types of treatments for OUD. In this manner, patients provided important insight to inform the selection of interventions to be evaluated, patient characteristics that may differentially impact the effects of the interventions, and the patient outcomes to be examined.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/AActiveOverdue
2020202120222023202420252026
First PostedFeb 5, 2020
Enrollment StartJul 15, 2020
Primary CompletionJun 30, 2025
Study CompletionJun 30, 2026
TodayJul 2, 2026
Enrollment to primary: 5.0 yearsPosted 6.4 years ago

Interventions

Psychosocial treatmentbehavioral

Participants randomly assigned to one of four psychosocial treatment conditions including cognitive behavioral therapy and a certified recovery specialist.