CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 28 enrolled
Drug / intervention
Active household UV water treatment device +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04258059
NCT04258059N/ACompleted

Wells and Enteric Disease Transmission - A Randomized Controlled Trial (WET- Trial)

Temple University·interventional·Posted Feb 6, 2020·Updated Sep 9, 2025

In Brief

A clinical study evaluating Active household UV water treatment device and Inactive household UV water treatment device for Gastrointestinal Infection and Respiratory Viral Infection. Completed, enrolled 28 participants across 1 site.

Detailed Summary

Approximately 40 million people in the US are served by private wells, many of which are untreated. The investigators estimate that 1.29 million cases of gastrointestinal illness (GI) per year are attributed to consuming water from untreated private wells in the US. These cases of GI can cause a significant burden in terms of health care costs and lost work/school days, as well as increased risk to developing longer term health complications. This impact is magnified when accounting for vulnerable populations such as children under the age of 5, the elderly and the immunocompromised. The investigators are preparing to conduct the first household randomized controlled trial (RCT) to investigate whether consuming well water treated by ultraviolet light (UV) compared to consuming untreated private well water decreases the incidence of self-reported gastrointestinal illness and respiratory infections in children under 5. The investigators will collect illness symptom data using a combination of weekly text messages and online illness questionnaires.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedFeb 6, 2020
Enrollment StartJun 30, 2020
Primary CompletionMay 1, 2022
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 6.4 years ago

Interventions

Active household UV water treatment devicedevice

This point-of-entry treatment device will use germicidal UV to treat all of the well water used in the home.

Inactive household UV water treatment devicedevice

This sham device will use a lamp not emitting germicidal UV.