CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 115 enrolled
Drug / intervention
Time Restricted Eating (TRE) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04259632
NCT04259632N/ACompleted

Prolonged Daily Fasting as a Viable Alternative to Caloric Restriction in At-Risk Obese Humans

University of Minnesota·interventional·Posted Feb 6, 2020·Updated Jan 23, 2026

In Brief

A clinical study evaluating Time Restricted Eating (TRE) and Caloric Restriction (CR) for Obesity. Completed, enrolled 115 participants across 1 site.

Detailed Summary

Purpose: Obesity is reaching epidemic proportions, affecting 36% of the adult population in the United States. There is intense interest in dietary management to treat obesity and its associated complications. The first line of obesity treatment is caloric restriction (CR), although recidivism is common. For moderate CR, attrition rates of 20% are often reported, therefore weight loss options beyond CR are urgently needed.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedFeb 6, 2020
Enrollment StartOct 15, 2020
Primary CompletionOct 12, 2023
Study CompletionDec 31, 2025
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 6.4 years ago

Interventions

Time Restricted Eating (TRE)behavioral

daily eating window restricted to 8 hours

Caloric Restriction (CR)behavioral

15% daily caloric deficient