At a glance
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Comparison of Efficacy of Premedication Between Dexmedetomidine and Midazolam Intranasal for the Prevention of Emergence Delirium in Children Undergoing Ophthalmic Surgery
In Brief
A Phase 4 clinical trial evaluating Intranasal dexmedetomidine and Intranasal Midazolam for Emergence Delirium. Completed, enrolled 66 participants across 1 site.
Detailed Summary
This study is a double-blind clinical trial, in pediatric patients aged 1-12 years with physical status ASA (American Society of Anesthesiology) 1 and 2 who underwent eye surgery under general anesthesia using Sevoflurane inhalation agents, in investigator institution during February-May 2019.. There were 64 children obtained by consecutive sampling, who underwent eye surgery in investigator institution during February-May 2019. The subjects then grouped into dexmedetomidine group and midazolam group. Effectiveness was assessed from Emergence Delirium (ED) events, recovery time, and post-premedication desaturation events. Data analysis using Chi Square test and Mann-Whitney test.
Study Details
Timeline
Interventions
subject will receive premedication with intranasal dexmedetomidine thirty minutes before induction
subject will receive premedication with intranasal midazolam thirty minutes before induction