CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 45 enrolled
Drug / intervention
20 mg MitoQ +2 moredrug
Likely dose
20 mg MitoQfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04267926
NCT04267926Phase 2Completed

MitoQ for Fatigue in Multiple Sclerosis: A Placebo Controlled Trial

VA Office of Research and Development·interventional·Posted Feb 13, 2020·Updated Apr 24, 2026

In Brief

A Phase 2 clinical trial evaluating 20 mg MitoQ, Placebo, and 1 other intervention for Multiple Sclerosis and Fatigue. Completed, enrolled 45 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether MS patients who receive Oral mitoquinone (MitoQ) have less fatigue than those receiving a placebo. A comparison between patient's fatigue scored at baseline and fatigue scored 12 weeks after drug initiation will assess if MitoQ has a significant change in fatigue.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedFeb 13, 2020
Enrollment StartApr 1, 2020
Primary CompletionOct 15, 2024
Study CompletionMar 31, 2026
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 6.4 years ago

Interventions

20 mg MitoQdrug

a third of subject will receive 20mg of oral MitoQ

Placebodrug

Subject will receive Placebo

40mg of MitoQdrug

a third of subjects will receive 40mg of MitoQ