CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 77 enrolled
Drug / intervention
Omega-3 fatty acid supplementdietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04268134
NCT04268134Phase 2Completed

Omega-3 Fatty Acids, Oxylipins, and Tolerance of Aromatase Inhibitor Therapy

University of Michigan Rogel Cancer Center·interventional·Posted Feb 13, 2020·Updated May 6, 2026

In Brief

A Phase 2 clinical trial evaluating Omega-3 fatty acid supplement for Breast Cancer. Completed, enrolled 77 participants across 1 site.

Detailed Summary

Aromatase inhibitor medications have been approved by the U.S Food and Drug Administration (FDA) for treatment of hormone receptor positive breast cancer. This treatment has been shown to be very effective for treating breast cancer. However, some patients have difficulty tolerating the treatment, and some even decide to stop treatment because of the side effects. Research has shown that over half of patients who had joint pain and stiffness when taking an aromatase inhibitor had an improvement in their symptoms when they took omega-3 fatty acid supplements. This study is being conducted to test whether having patients start to take an omega-3 fatty acid supplement soon after they starting taking an aromatase inhibitor medicine will reduce the likelihood that they will have bothersome symptoms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBreast Cancer
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedFeb 13, 2020
Enrollment StartJul 28, 2020
Primary CompletionFeb 27, 2024
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 6.4 years ago

Interventions

Omega-3 fatty acid supplementdietary

4 capsules taken by mouth each day for 24 weeks (starting at the week 12 visit).