CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 61 enrolled
Drug / intervention
Thromboelastographyother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04268940
NCT04268940N/ACompleted
CompareCT.gov

Thrombo-Elastography Guided Management of ECMO

Damian Ratano·observational·Posted Feb 13, 2020·Updated Jan 16, 2026

In Brief

An observational study evaluating Thromboelastography for Extracorporeal Circulation of Blood; Thrombocytopenia. Completed, enrolled 61 participants across 1 site.

Detailed Summary

Anticoagulation and coagulation management during ECMO is a challenge. Bleeding and clotting are major sources of morbidity and mortality. The currently used strategies are of poor evidence. This observational study wants to evaluate the use of automated thromboelastography (TEG 6s) to guide the management of coagulation and anticoagulation in patients supported by ECMO

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsExtracorporeal Circulation of Blood; Thrombocytopenia
CountriesCanada
CollaboratorsThe Physicians' Services Incorporated Foundation

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedFeb 13, 2020
Enrollment StartJun 3, 2020
Primary CompletionJun 4, 2021
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 6.4 years ago

Interventions

Thromboelastographyother

Thromboelastography (TEG 6s, global hemostasis cartridge) will be performed before ECMO insertion and at different time-points during the course of ECMO. In parallel a full coagulation work-up (aPTT, prothrombin time \[PT\], anti-Xa, activated clotting time\[ACT\], platelets count, d-dimers, von Willebrand panel and fibrinogen) will be measured simultaneously with each TEG.