CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 25 enrolled
Drug / intervention
Platelet- and extracellular vesicle-rich plasma +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04281901
NCT04281901N/ACompleted

Efficacy of Platelet- and Extracellular Vesicle-rich Plasma for the Treatment of Chronically Inflamed Post-surgical Temporal Bone Cavities: a Randomised Controlled Clinical Study

University Medical Centre Ljubljana·interventional·Posted Feb 24, 2020·Updated Aug 3, 2021

In Brief

A clinical study evaluating Platelet- and extracellular vesicle-rich plasma and Standard conservative treatment for Otitis Media Chronic and Temporal Bone. Completed, enrolled 25 participants across 1 site.

Detailed Summary

This clinical study evaluates the efficacy of the autologous blood-derived product called platelet- and extracellular vesicle-rich plasma (PVRP) for the treatment of chronically inflamed post-surgical temporal bone cavities. Half of the participants will be treated with platelet- and extracellular vesicle-rich plasma and another half with standard nonsurgical measures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSlovenia

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedFeb 24, 2020
Enrollment StartMar 20, 2019
Primary CompletionApr 15, 2020
Study CompletionOct 14, 2020
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 6.4 years ago

Interventions

Platelet- and extracellular vesicle-rich plasmadrug

ear wick soaked in platelet- and extracellular vesicle-rich plasma

Standard conservative treatmentdrug

standard conservative measures, including antimicrobials, antiseptics and aural toilette for treating a chronically inflamed radical cavity.