CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 23 enrolled
Drug / intervention
Ganaxolonedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04285346
NCT04285346Phase 2Completed

A Phase 2 Open-label 12-Week Trial of Adjunctive Ganaxolone Treatment (Part A) in Tuberous Sclerosis Complex-related Epilepsy Followed by Long-term Treatment (Part B)

Marinus Pharmaceuticals·interventional·Posted Feb 26, 2020·Updated Apr 4, 2023

In Brief

A Phase 2 clinical trial evaluating Ganaxolone for Tuberous Sclerosis. Completed, enrolled 23 participants across 7 sites.

Detailed Summary

To assess preliminary safety and efficacy of ganaxolone as adjunctive therapy for the treatment of primary seizure types in patients with genetically- or clinically-confirmed TSC-related epilepsy through the end of the 12 week treatment period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedFeb 26, 2020
Enrollment StartApr 8, 2020
Primary CompletionJun 25, 2021
Study CompletionAug 30, 2022
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 6.4 years ago

Interventions

Ganaxolonedrug

titration followed by maintenance and extension period