CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 58 enrolled
Drug / intervention
Experimental Dentifrice: Stannous Fluoride +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04290624
NCT04290624Phase 4Completed

A Randomized, Controlled Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health, Compared to Existing Oral Hygiene, in a Population of Partial Denture Wearers With Generalized Mild-moderate Plaque-induced Gingivitis

HALEON·interventional·Posted Mar 2, 2020·Updated Nov 18, 2023

In Brief

A Phase 4 clinical trial evaluating Experimental Dentifrice: Stannous Fluoride, COREGA Denture Foaming Cleanser, and 1 other intervention for Gingivitis. Completed, enrolled 58 participants across 1 site.

Detailed Summary

The purpose of this study is to investigate the effectiveness of usage of a range of oral products (toothpaste, mouth rinse, denture cleanser) on the oral health of partial denture wearers compared to existing oral hygiene habits.The hypothesis is that there is no treatment difference in the oral health when using the range of products for 12 weeks compared to no intervention.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGingivitis
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedMar 2, 2020
Enrollment StartOct 14, 2020
Primary CompletionFeb 24, 2022
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 6.3 years ago

Interventions

Experimental Dentifrice: Stannous Fluorideother

Participants will be instructed to dose the toothbrush provided with a strip of dentifrice (a full brush head) on each brushing occasion containing 0.454% w/w Stannous fluoride for 2 minutes twice daily (morning and evening) for 12 weeks.

COREGA Denture Foaming Cleanserdevice

Participant will clean their denture using 2 pumps of the denture cleansing foam and a denture cleaning brush for 90 timed seconds outside of the mouth twice daily (morning and evening) for 12 weeks.

Mouth rinse: Sodium Fluorideother

Participants will take 10 ml of the mouth rinse containing 90 ppm sodium fluoride and swished around the mouth for 1 minute twice daily (morning and evening) for 12 weeks.