CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,672 enrolled
Drug / intervention
Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs) +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04290975
NCT04290975N/ACompleted

Bridging the Childhood Epilepsy Treatment Gap in Africa (BRIDGE)

Vanderbilt University Medical Center·interventional·Posted Mar 2, 2020·Updated Feb 20, 2026

In Brief

A clinical study evaluating Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs) and Enhanced usual care for epilepsy (EUC) for Epilepsy. Completed, enrolled 1,672 participants across 3 sites.

Detailed Summary

About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel intervention shifting childhood epilepsy care to epilepsy-trained community health extension workers in an effort to close the epilepsy treatment gap. This research will provide information to help extend epilepsy treatment to children in LMICs and worldwide who suffer from untreated seizures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEpilepsy
CountriesNigeria

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedMar 2, 2020
Enrollment StartJun 16, 2020
Primary CompletionMay 31, 2024
Study CompletionJul 15, 2025
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 6.3 years ago

Interventions

Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs)other

Children with previously untreated epilepsy, identified via community-based screening and diagnositic evaluations, receive epilepsy care (including anti-seizure medication management) from epilepsy-trained community health workers (CHWs).

Enhanced usual care for epilepsy (EUC)other

Children with previously untreated epilepsy, identified via community-based screening and diagnostic evaluations, receive epilepsy care by physicians, as routinely done in Nigeria. The usual physician care is enhanced by community health workers (CHWs), who do not participate in the child's epilepsy care, but who help families navigate the healthcare system.