At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 15 enrolled
Drug / intervention
Cocaine HCl +1 moredrug
Likely dose
Cocaine HCl 3 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Neurobehavioral Mechanisms of Cocaine Choice
In Brief
A Early Phase 1 clinical trial evaluating Money and Cocaine HCl for Cocaine Use Disorder. Completed, enrolled 15 participants across 1 site.
Detailed Summary
The objective of this protocol is to use a drug-vs-money choice task, reinforcement learning modeling and fMRI to determine the neurobehavioral and neurobiological decision-making "profile" associated with the decision to take cocaine and the reduced cocaine choice that occurs during a behavioral intervention (alternative money reinforcer) that models contingency management.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine Use Disorder
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)
Timeline
Early Ph 1CompletedFinished
2020202120222023202420252026
First PostedMar 2020
Enrollment StartJan 2021
Primary CompletionFeb 2025
TodayJul 2026
First PostedMar 5, 2020
Enrollment StartJan 15, 2021
Primary CompletionFeb 1, 2025
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 6.3 years ago
Interventions
Moneybehavioral
Three money values offered as alternatives to cocaine.
Cocaine HCldrug
3 mg/70 kg is available as an alternative to money.