CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 20 enrolled
Drug / intervention
Tobramycin Powder +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04297631
NCT04297631Phase 4Completed

Prospective Study Investigating Antibiotic Elution From Free Intra-articular Vancomycin and Tobramycin After Cementless Total Knee Arthroplasty

Washington University School of Medicine·interventional·Posted Mar 5, 2020·Updated Oct 5, 2021

In Brief

A Phase 4 clinical trial evaluating Tobramycin Powder and Vancomyscin for Antibotics in Cementless Knees. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The purpose of the study is to determine the intra-articular concentration of vancomycin and tobramycin after administration of vancomycin and tobramycin powder in primary cementless total knee arthroplasty and determine the serum concentrations of these antibiotics postoperatively.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedMar 5, 2020
Enrollment StartFeb 14, 2020
Primary CompletionAug 1, 2020
Study CompletionNov 1, 2020
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 6.3 years ago

Interventions

Tobramycin Powderdrug

Everyone gets tobramycin powder.

Vancomyscindevice

Everyone gets the vancomyscin powder.