CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 160 enrolled
Drug / intervention
epidural bupivacaine 0.05% +5 moredrug
Likely dose
/hydromorphone 0.05mg/mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04300231
NCT04300231Phase 3Completed

Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy

Indiana University·interventional·Posted Mar 9, 2020·Updated Feb 10, 2025

In Brief

A Phase 3 clinical trial evaluating epidural bupivacaine 0.05%, Liposomal bupivacaine, and 4 other interventions for Cystectomy. Completed, enrolled 160 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the difference between four different pain control methods in patients who will be having a cystectomy surgery (surgical removal of the bladder).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCystectomy
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedMar 9, 2020
Enrollment StartOct 22, 2019
Primary CompletionDec 23, 2021
Study CompletionDec 24, 2021
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 6.3 years ago

Interventions

epidural bupivacaine 0.05%drug

Mix of epidural bupivacaine 0.05% and hydromorphone 0.05mg/ml will be given using PCEA.

Liposomal bupivacainedrug

20 ml

bupivacaine 0.125%drug

40 mL

bupivacaine 0.5%drug

60 mL

/hydromorphone 0.05mg/mldrug

Mix of epidural bupivacaine 0.05% and hydromorphone 0.05mg/ml will be given using PCEA.

injectable salinedrug

40 mL