CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Mindfulness Based Stress Reduction (MBSR) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04302493
NCT04302493N/ACompleted

Mindfulness Matters: The Impact of Mindfulness Based Stress Reduction on Post-Stroke Cognition

Johns Hopkins University·interventional·Posted Mar 10, 2020·Updated Dec 20, 2024

In Brief

A clinical study evaluating Mindfulness Based Stress Reduction (MBSR) and Stroke Support Group (SSG) for Stroke and 3 related conditions. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The investigators don't fully understand how, regardless of the size or location in the brain, minor strokes can result in significant problems with focus, attention, and multi-tasking that prevent individuals from returning to an active lifestyle, and negatively impact quality of life; but the investigators' preliminary data using magnetoencephalography (MEG) suggest that there may be disruption of the neuronal network and abnormal frontal lobe activity in the brain after stroke. Mindfulness Based Stress Reduction (MBSR) is effective at treating frontal lobe dysfunction in the form of anxiety and depression occurring during the chronic phase of stroke recovery. The aim of this study is to use MBSR to improve other forms of frontal lobe dysfunction (cognitive outcomes) during the subacute phase of recovery, when patients are making critical decisions regarding patients' ability to return to work or live independently; and to use MEG, a tool capable of imaging brain activity and neuronal networks, to understand the brain changes that correspond to improvement after treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedMar 10, 2020
Enrollment StartJan 1, 2021
Primary CompletionJun 1, 2023
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 6.3 years ago

Interventions

Mindfulness Based Stress Reduction (MBSR)behavioral

Participants randomized to the MBSR arm will undergo a standard 8 week course of MBSR taught by a psychologist trained in the MBSR protocol and encouraged to engage in additional individual mindfulness sessions using a cell phone application.

Stroke Support Group (SSG)behavioral

As a control group, participants randomized to the SSG arm will participate in 8 weeks of weekly Stroke Support Group sessions to experience activity and socialization without additional mindfulness training.