CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 360 enrolled
Drug / intervention
Active drug +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04311099
NCT04311099Phase 4Completed

Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block in Minimally Invasive Colon Surgery: A Randomized Controlled Multicentre Clinical Trial

Claus Anders Bertelsen, PhD, MD·interventional·Posted Mar 17, 2020·Updated Aug 7, 2025

In Brief

A Phase 4 clinical trial evaluating Active drug, Placebo, and 4 other interventions for Pain, Postoperative and 5 related conditions. Completed, enrolled 360 participants across 5 sites.

Detailed Summary

The purpose of the trial is to identify the "most simple non-inferior of three different methods", placebo, laparoscopic assisted transverse abdominal plane block (L-TAP) and ultrasound guided TAP block (US-TAP), using postoperative opioid consumption as a measure of efficacy in patients undergoing elective minimally invasive colon surgery in an ERAS setting. Postoperative pain scores and length of stay (LOS) will also be measured. The simplicity of the three methods is ranked as: 1) placebo, 2) L-TAP and 3) US-TAP.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesDenmark
Collaborators--

Timeline

Phase 4CompletedFinished
202120222023202420252026
First PostedMar 17, 2020
Enrollment StartJan 14, 2021
Primary CompletionFeb 8, 2024
Study CompletionMar 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 6.3 years ago

Interventions

Active drugdrug

Injection of Ropivacaine

Placebodrug

Injection of Saline solution

Injection of Ropivacaine - Ultrasound-guided transverse abdominal plane blockprocedure

Lateral ultrasound-guided transverse abdominal plane block 40 ml ropivacaine 2 mg / ml

Injection of Ropivacaine - Laparoscopic assisted transverse abdominal plane blockprocedure

Laparoscopic assisted subcostal transverse abdominal plane block 40 ml ropivacaine 2 mg / ml

Injection of placebo - Ultrasound-guided transverse abdominal plane blockprocedure

Lateral ultrasound-guided transverse abdominal plane block with saline solution

Injection of placebo - Laparoscopic assisted transverse abdominal plane blockprocedure

Laparoscopic assisted subcostal transverse abdominal plane block with saline solution