At a glance
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Valsalva Urethral Profile (VUP) : a New Measure to Assess Stress Urinary Incontinence in Women
In Brief
A clinical study evaluating Maximum urethral closure pressure during Valsalva (v-MUCP) for Stress Urinary Incontinence. Completed, enrolled 695 participants.
Detailed Summary
Clinical and paraclinical appraisal of stress urinary incontinence (SUI) is mainly based on the assessment of pelvic floor muscles (PFM) contraction and urethral mobility, the measurement of the maximum urethral closure pressure (MUCP) at rest by urethral pressure profilometry (UPP) and the measurement of the Valsalva leak point pressure (VLPP). Currently, MUCP and VLPP cannot be used for diagnosing SUI because they appear to be moderately correlated with the severity of SUI. The lack of a specific SUI biomarker could be the explanation for the poor predictive value of urodynamics and the ongoing debate on whether urodynamic testing before surgery has benefits. Our main objective was to study the value of a new urodynamic parameter in the diagnosis of female SUI: the Valsalva urethral profile (VUP)
Study Details
Timeline
Interventions
v-MUCP measurement was performed for all patients referred for urodynamic exploration of the lower urinary tract