At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure
In Brief
A Phase 4 clinical trial evaluating prp injection, Anrecta, and 2 other interventions for Anal Fissure Chronic and PRP. Completed, enrolled 41 participants across 1 site.
Detailed Summary
Autologous PRP currently has many uses in surgical and medical therapy. Compared with other regenerative therapies, PRP is easy-to-prepare, low-cost, and does not require complex equipment. The use of autologous PRP avoids immunological side effects. Data is lacking on the use of PRP in the treatment of anal fissure. This study evaluated PRP as an alternative medical treatment for chronic anal fissures.
Study Details
Timeline
Interventions
PRP was injected locally in the anal fissure area and glyceryl trinitrate was administered twice daily in the perianal region as in the control group.
self-administered topical glyceryl trinitrate (anrecta), in the perianal area twice a day
participants were told to take a hot water sitz bath once a day
The study participants were told to eat a fiber-rich diet and to drink least 2 liters of water daily