CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 133 enrolled
Drug / intervention
Hypoglossal Nerve Stimulationdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04322097
NCT04322097N/ACompleted
CompareCT.gov

Characterizing Mechanisms of Upper Airway Obstruction During Drug-Induced Sleep Endoscopy (DISE)

University of Pennsylvania·interventional·Posted Mar 26, 2020·Updated Jan 21, 2026

In Brief

A clinical study evaluating Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea. Completed, enrolled 133 participants across 1 site.

Detailed Summary

The current study is designed to examine underlying mechanisms of action of lingual muscles in the maintenance of airway patency during sleep. The investigators' major hypothesis is that specific tongue muscles are responsible for relieving upper airway obstruction during sleep.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObstructive Sleep Apnea
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedMar 26, 2020
Enrollment StartJun 3, 2020
Primary CompletionMay 10, 2024
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 6.3 years ago

Interventions

Hypoglossal Nerve Stimulationdevice

On/off responses will be assessed both during Drug-Induced Sleep Endoscopy (DISE) and Polysomnography (PSG).