CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 175 enrolled
Drug / intervention
Transnasal Humidified Rapid-Insufflation Ventilatory Echangedevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04322994
NCT04322994N/ACompleted

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Populations: A Randomized Prospective Multi-Site Trial

Stanford University·interventional·Posted Mar 26, 2020·Updated Mar 27, 2025

In Brief

A clinical study evaluating Transnasal Humidified Rapid-Insufflation Ventilatory Echange for Oxygen Deficiency and 3 related conditions. Completed, enrolled 175 participants across 5 sites.

Detailed Summary

THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can prevent desaturation events in children under anesthesia and improve the outcomes of that surgery.

Study Details

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedMar 26, 2020
Enrollment StartOct 21, 2020
Primary CompletionJan 19, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 6.3 years ago

Interventions

Transnasal Humidified Rapid-Insufflation Ventilatory Echangedevice

The use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.