At a glance
ClinicalIndex Comparison RecordN/ACompleted· 218 enrolled
Drug / intervention
Esomeprazole 40mg +1 moredrug
Likely dose
Esomeprazole 40mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Impacts of On-demand Versus Continuous Esomeprazole Therapy on the Symptom Control and Histological Changes of Metaplastic Esophageal Epithelium in Patients With Barrett's Esophagus (EsoBE) - a Multicentre Randomized Controlled Trial
In Brief
A clinical study evaluating Esomeprazole 40mg and Esomeprazole for Barrett Esophagus and 3 related conditions. Completed, enrolled 218 participants.
Detailed Summary
On-demand PPI therapy is feasible for the long-term treatment of patients with Barrett's esophagus.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBarrett Esophagus, Proton Pump Inhibitor, Symptom, Reflux
Countries--
Collaborators--
Timeline
N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartFeb 2010
Primary CompletionFeb 2019
Study CompletionDec 2019
First PostedApr 2020
TodayJul 2026
First PostedApr 1, 2020
Enrollment StartFeb 2, 2010
Primary CompletionFeb 13, 2019
Study CompletionDec 8, 2019
TodayJul 2, 2026
Enrollment to primary: 9.0 yearsPosted 6.3 years ago
Interventions
Esomeprazole 40mgdrug
On-demand Esomeprazole 40 mg QD
Esomeprazoledrug
Continuous Esomeprazole 40 mg QD