CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 3,411 enrolled
Drug / intervention
MR or M-M-R II ® vaccine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04333732
NCT04333732Phase 3Completed

An International, Multi-site, Bayesian Platform Adaptive, Randomized, Placebo-controlled Trial Assessing the Effectiveness of Candidate Agents in Mitigating COVID-19 Disease in Adults

Washington University School of Medicine·interventional·Posted Apr 3, 2020·Updated Mar 26, 2024

In Brief

A Phase 3 clinical trial evaluating MR or M-M-R II ® vaccine and Placebo for COVID 19. Completed, enrolled 3,411 participants across 17 sites in 5 countries.

Detailed Summary

The objective of CROWN CORONATION is the prevention of symptomatic COVID-19 by using combinations of approved and safe repurposed interventions, with complementary mechanisms of action.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID 19
CountriesGhana, South Africa, United Kingdom, United States, Zambia

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedApr 3, 2020
Enrollment StartSep 4, 2020
Primary CompletionAug 10, 2021
Study CompletionDec 3, 2021
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 6.2 years ago

Interventions

MR or M-M-R II ® vaccinedrug

Education and surveillance plus MR or M-M-R II ® vaccine

Placebodrug

Placebo injection