At a glance
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Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure (OSPREY-AHF)
In Brief
A clinical study evaluating Oral Sodium Chloride and Placebo for Volume Overload. Active but no longer recruiting, targeting 67 participants across 1 site.
Detailed Summary
The investigators are proposing a prospective, randomized, double blinded, placebo-controlled single center study evaluating the role of co-administration of oral sodium chloride (NaCl) with intravenous diuretics in patients hospitalized with acute decompensated heart failure. The investigators are approaching this study with the hypothesis that the use of oral sodium chloride leads to improved effective diuresis (as measured by weight loss) and renal function as compared to placebo in patients hospitalized with acute decompensated heart failure undergoing aggressive intravenous diuretic therapy.
Study Details
Timeline
Interventions
Subjects will be randomized to receive 2 grams oral Sodium Chloride three times daily with meals for approximately 4 days
Subjects will be randomized to receive a placebo three times daily with meals for approximately 4 days.