CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 113 enrolled
Drug / intervention
EMLA Cream +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04337814
NCT04337814N/ACompleted

The Effect of Combined Oral and Topical Analgesics to Reduce Pain Perception During Electromyography in Pediatric Population-A Randomized Controlled Trial

Aga Khan University Hospital, Pakistan·interventional·Posted Apr 8, 2020·Updated Feb 28, 2023

In Brief

A clinical study evaluating EMLA Cream, Ibuprofen, and 2 other interventions for Pain Perception. Completed, enrolled 113 participants across 1 site.

Detailed Summary

Electromyography (EMG) is a useful test for diagnosis and monitoring of lower motor neuron disorders. It is mostly done in conjunction with a Nerve Conduction Study (NCS). Like other invasive medical procedures; electrodiagnostic tests have been known to cause iatrogenic pain for the patient, the intensity of which varies from person to person. Multiple modifiable as well as non-modifiable risk factors associated with EMG pain have been described in literature.Various approaches targeting different mechanisms of pain perception have been tested to make this procedure comfortable for the patients. These approaches range from simple distraction techniques to the use of topical and oral analgesics.Most of these studies have looked at adult population which has, supposedly, better pain tolerance as compared to children. Data on EMG associated pain in pediatric population is scant. This trial will assess the effect of combined oral and topical analgesics to reduce pain perception during NCS and EMG tests in the pediatric population.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain Perception
CountriesPakistan
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedApr 8, 2020
Enrollment StartDec 30, 2019
Primary CompletionJun 27, 2022
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 6.2 years ago

Interventions

EMLA Creamdrug

Topical anaesthetic cream

Ibuprofendrug

Oral analgesic syrup (non-steroidal anti inflammatory drug)

Placebo syrupdrug

Placebo syrup similar to Ibuprofen

Placebo creamdrug

Placebo cream similar to EMLA