CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 50 enrolled
Drug / intervention
Abbreviated MRI protocol: initial experience with Dotarem® (Gadoterate Meglumine)drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04341129
NCT04341129Early Ph 1Completed

Abbreviated MRI Protocol: Initial Experience With Dotarem® (Gadoterate Meglumine)

University of Chicago·interventional·Posted Apr 10, 2020·Updated Dec 5, 2023

In Brief

A Early Phase 1 clinical trial evaluating Abbreviated MRI protocol: initial experience with Dotarem® (Gadoterate Meglumine) for Breast Neoplasms and 3 related conditions. Completed, enrolled 50 participants across 1 site.

Detailed Summary

Standard breast MRI studies often have lengthy protocols that make them inherently expensive and time-consuming. Several studies of the use of abbreviated MRI protocols have shown that the shorter protocols have diagnostic accuracy comparable to that of the conventional full MRI protocol. There are also promising results of ultrafast DCE-MRI studies with shorter breast MRI protocols that provide not only morphologic but also valuable kinetic information about a lesion. The shorter imaging times achieved with the abbreviated and the ultrafast DCE-MRI protocols have the potential to increase efficiency and lower cost by decreasing time in the MRI suite, which in turn may make breast MRI accessible for population-based mass screening. The focus of the proposed research is the investigation of an abbreviated MRI protocol with ultrafast imaging using Dotarem® (Gadoterate Meglumine).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsGuerbet

Timeline

Early Ph 1CompletedFinished
202120222023202420252026
First PostedApr 10, 2020
Enrollment StartJul 13, 2020
Primary CompletionJun 30, 2023
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 6.2 years ago

Interventions

Abbreviated MRI protocol: initial experience with Dotarem® (Gadoterate Meglumine)drug

To test the diagnostic effectiveness of an abbreviated MRI to a full MRI in the evaluation of breast lesions using Dotarem