CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 539 enrolled
Drug / intervention
Point-of-care viral load testing and tenofovir adherence testingcombination
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04341779
NCT04341779N/AActive

Simplifying Treatment and Monitoring for HIV (STREAM HIV): Point-of-Care Urine Tenofovir Adherence and Viral Load Testing to Improve HIV Outcomes in South Africa

University of Washington·interventional·Posted Apr 10, 2020·Updated Feb 19, 2026

In Brief

A clinical study evaluating Point-of-care viral load testing and tenofovir adherence testing for HIV/AIDS and HIV-1-infection. Active but no longer recruiting, targeting 539 participants across 1 site.

Detailed Summary

This study seeks to determine the clinical efficacy and cost effectiveness of implementing an integrated model for HIV monitoring using point of care (POC) tenofovir (TFV) adherence testing and POC viral load (VL) monitoring in improving ART adherence, maintaining durable VL suppression, and improving retention in care among HIV-positive individuals initiating first-line tenofovir disoproxil fumarate (TDF)-based ART in South Africa.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSouth Africa

Timeline

N/AActive
2021202220232024202520262027
First PostedApr 10, 2020
Enrollment StartFeb 4, 2021
Primary CompletionJun 30, 2025
Study CompletionDec 31, 2026
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 6.2 years ago

Interventions

Point-of-care viral load testing and tenofovir adherence testingcombination

Point-of-care testing of HIV viral load and tenofovir, and providing same day results to participants