CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 4,461 enrolled
Drug / intervention
Targeted Indoor Residual Spraying (TIRS)other
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04343521
NCT04343521N/ACompleted
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Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne Diseases

Emory University·interventional·Posted Apr 13, 2020·Updated Sep 18, 2025

In Brief

A clinical study evaluating Targeted Indoor Residual Spraying (TIRS) for Aedes-borne Diseases and 3 related conditions. Completed, enrolled 4,461 participants across 1 site.

Detailed Summary

The objective of this trial is evaluate the efficacy of Targeted Indoor Residual Spraying (TIRS) in preventing symptomatic disease caused by Aedes-borne diseases (ABDs) in children 2 to 15 years of age in the city of Merida, Yucatan State, Mexico.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAedes-borne Diseases, Dengue, Chikungunya, Zika
CountriesMexico
CollaboratorsNational Institute of Allergy and Infectious Diseases (NIAID)

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedApr 13, 2020
Enrollment StartNov 3, 2020
Primary CompletionApr 28, 2024
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 6.2 years ago

Interventions

Targeted Indoor Residual Spraying (TIRS)other

Spraying of insecticide Actellic 300CS will start in May or June extending for 1 to 2 months. Residents will be asked to temporarily leave the house during treatment and wait half an hour to one hour for the product to dry before re-entering the house. Insecticide application will follow strict protocol developed by the Centers for Disease Control and Prevention (CDC), Emory University, and the Universidad Autónoma de Yucatán.