CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 47 enrolled
Drug / intervention
L-ascorbic acid +1 moredrug
Likely dose
L-ascorbic acid 50 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04344184
NCT04344184Phase 2Completed

SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI)

Virginia Commonwealth University·interventional·Posted Apr 14, 2020·Updated Apr 4, 2024

In Brief

A Phase 2 clinical trial evaluating L-ascorbic acid and Placebo for COVID-19 and 2 related conditions. Completed, enrolled 47 participants across 1 site.

Detailed Summary

This study will evaluate the safety of a 96-hour intravenous vitamin C infusion protocol (50 mg/kg every 6 hours) in patients with hypoxemia and suspected COVID-19.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedApr 14, 2020
Enrollment StartDec 18, 2020
Primary CompletionJun 10, 2022
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 6.2 years ago

Interventions

L-ascorbic aciddrug

50 mg/kg intravenous vitamin C infusion every 6 hours for up to 96 hours

Placeboother

Dextrose 5% Water