CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 79 enrolled
Drug / intervention
Platelet Rich Plasmadevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04351087
NCT04351087N/ACompleted
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Microfragmented Adipose Tissue Versus Platelet-rich Plasma for Knee Osteoarthritis: a Randomized Comparative Trial

Ohio State University·interventional·Posted Apr 17, 2020·Updated Aug 9, 2024

In Brief

A clinical study evaluating Platelet Rich Plasma for Osteoarthritis, Knee and 2 related conditions. Completed, enrolled 79 participants across 1 site.

Detailed Summary

The study aims to conduct a randomized trial comparing the clinical outcomes of PRP (standard intervention) versus Microfragmented adipose tissue (investigational) for the treatment of knee osteoarthritis. Hypothesis: Both interventions will result in significant improvement in patient-reported outcomes. We hypothesize that Microfragmented adipose tissue will provide superior outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis, Knee, Microfragmented Adipose Tissue, Platelet-Rich Plasma
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedApr 17, 2020
Enrollment StartMar 3, 2020
Primary CompletionJul 5, 2022
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 6.2 years ago

Interventions

Platelet Rich Plasmadevice

Platelet rich plasma: 157cc of whole blood will be collected, processed, and injected into the knee joint under sterile technique using ultrasound-guidance. Microfragmented adipose tissue: Adipose will be aspirated from the subcutaneous tissue of the buttock or abdomen, processed, and injected into the knee joint under sterile technique using ultrasound-guidance.