CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 227 enrolled
Drug / intervention
Gimsilumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04351243
NCT04351243Phase 2Completed

A Multi-Center, Adaptive, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)

Kinevant Sciences GmbH·interventional·Posted Apr 17, 2020·Updated Dec 14, 2021

In Brief

A Phase 2 clinical trial evaluating Gimsilumab and Placebo for COVID-19. Completed, enrolled 227 participants across 33 sites.

Detailed Summary

Study KIN-1901-2001 is a multi-center, adaptive, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of gimsilumab in subjects with lung injury or acute respiratory distress syndrome (ARDS) secondary to COVID-19.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID-19
CountriesUnited States

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedApr 17, 2020
Enrollment StartApr 15, 2020
Primary CompletionDec 1, 2020
Study CompletionApr 1, 2021
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 6.2 years ago

Interventions

Gimsilumabdrug

Gimsilumab is a fully human monoclonal antibody (mAb).

Placebodrug

Normal saline