CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 562 enrolled
Drug / intervention
Ofatumumabbiological
Likely dose
Ofatumumab 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04353492
NCT04353492Phase 3Completed

A Single-arm, Prospective, Multicentre, Open-label Study to Evaluate Ofatumumab Treatment Effectiveness and Patient-reported Outcomes (PRO) in Patients With Relapsing Multiple Sclerosis (RMS) Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod

Novartis Pharmaceuticals·interventional·Posted Apr 20, 2020·Updated Apr 9, 2026

In Brief

A Phase 3 clinical trial evaluating Ofatumumab for Relapsing Multiple Sclerosis. Completed, enrolled 562 participants across 123 sites in 27 countries.

Detailed Summary

Open-label study to evaluate the effectiveness of treatment with ofatumumab in subjects transitioning from any fumarate-based RMS approved therapy or fingolimod due to breakthrough disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Austria, Belgium, Bulgaria, Canada, Czechia, Estonia, Germany, Greece, Hungary, Italy, Latvia, Lebanon, Mexico, Norway, Poland, Portugal, Russia, Saudi Arabia, Slovakia, Slovenia, Spain, Switzerland, Turkey (Türkiye), United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedApr 20, 2020
Enrollment StartJul 14, 2020
Primary CompletionOct 9, 2024
Study CompletionMar 11, 2025
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 6.2 years ago

Interventions

Ofatumumabbiological

Subjects will receive ofatumumab injections in an autoinjector (AI) for subcutaneous administration containing 20 mg ofatumumab (50 mg/ml, 0.4 ml content)