CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 131 enrolled
Drug / intervention
anti-SARS-CoV-2 convalescent plasmabiological
Likely dose
anti-SARS-CoV-2 convalescent plasma 2 unitsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04354831
NCT04354831Phase 2Completed

An Open Label, Phase 2 Study Evaluating the Efficacy and Safety of High-Titer Anti-SARS-CoV-2 Plasma in Hospitalized Patients With COVID-19 Infection

Medical College of Wisconsin·interventional·Posted Apr 21, 2020·Updated Apr 10, 2024

In Brief

A Phase 2 clinical trial evaluating anti-SARS-CoV-2 convalescent plasma for COVID-19. Completed, enrolled 131 participants across 1 site.

Detailed Summary

This is a Phase II study. This research study is being conducted to use convalescent donor plasma in seriously ill patients who have COVID-19.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID-19
CountriesUnited States
CollaboratorsFroedtert Hospital

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedApr 21, 2020
Enrollment StartMay 11, 2020
Primary CompletionFeb 10, 2021
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 6.2 years ago

Interventions

anti-SARS-CoV-2 convalescent plasmabiological

* SARS-CoV-2 convalescent plasma (1-2 units; \~200-400 mL maximum dose as 7 ml/kg adjusted IBW ) * Study drug will be administered as a single intravenous infusion