CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 312 enrolled
Drug / intervention
ICA (Invasive Coronary Angiography) +3 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04356027
NCT04356027N/ACompleted

Validation of OCT-based FUnctional diagnoSIs of corONary Stenosis (FUSION)

Abbott Medical Devices·observational·Posted Apr 21, 2020·Updated Feb 21, 2025

In Brief

An observational study evaluating ICA (Invasive Coronary Angiography), OCT, and 2 other interventions for Coronary Artery Disease and Coronary Stenosis. Completed, enrolled 312 participants across 28 sites.

Detailed Summary

The purpose of the FUSION study is to validate the diagnostic performance of Virtual Flow Reserve (VFR) by comparing it against a reference standard, fractional flow reserve (FFR).

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedApr 21, 2020
Enrollment StartJun 26, 2020
Primary CompletionOct 15, 2021
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 6.2 years ago

Interventions

ICA (Invasive Coronary Angiography)procedure

Patients will undergo a Pre-PCI Angiography

OCTprocedure

OCT pullback images will be collected pre-PCI and (optional) post-PCI procedure

FFRprocedure

FFR will be measured

VFR Analysisother

VFR will be calculated offline using the OCT pullback images